P-OGC25 Prognostic significance of extracapsular lymph node involvement after gastrectomy for gastric adenocarcinoma

Abstract Background Lymph node involvement is a key prognostic indicator in gastric adenocarcinoma. Little known of the impact extracapsular lymph (LNI) upon prognosis patients undergoing curative resection cancer. The aim this study was to assess incidence and significance LNI gastrectomy for Methods Consecutive who underwent subtotal or total with intent adenocarcinoma stomach gastro-oesophageal junction single, high-volume U.K. centre between 2010 2018 were identified from contemporaneously maintained database. Patients pN0 status on final histology those died in-hospital excluded analysis. Factors associated survival studied univariable multivariable cox regression A p value < 0.05 deemed significant. Results included 235 patients. median (IQR) 32 (24-43) nodes resected 4 (1-9) positive. Of them, 123 (52%) analysis R1 (p = 0.001), p/ypT stage p/ypN 0.001) 0.001). Median among had 19 months versus 49 did not Extracapsular an independent predictor 0.535). Conclusions poor gastrectomy. However, it patient population.